Übersichtsarbeit
CRISPR/Cas9-based strategies for effective control of Spodoptera frugiperda in maize: a review of precision gene editing approaches
Basit, Abdul; Mobarak, Syed Husne; Liu, Tong-Xian
Entomologia Generalis Volume 45 Number 3 (2025), p. 651 - 666
veröffentlicht: Aug 19, 2025
Online veröffentlicht: Jun 2, 2025
Manuskript akzeptiert: Apr 27, 2025
Manuskript-Revision erhalten: Apr 13, 2025
Manuskript-Revision angefordert: Mar 8, 2025
Manuskript erhalten: Jan 10, 2025
Open Access (Arbeit kann kostenlos heruntergeladen werden)
Abstract
Fall armyworm (Spodoptera frugiperda) is a highly abundant and damaging pest and is responsible for causing significant destruction to agricultural crops globally. Chemical control methods, like insecticides, have become less effective as the pest adapts to accommodate a variety of chemical agents. Genetically modified maize plants producing Bacillus thuringiensis (Bt) proteins like Cry1F have been used to manage infestations. However, the emergence of Cry1F resistance in Cry1F–susceptible fall armyworm populations poses additional challenges to pest control. In recent years, CRISPR/Cas9 genome-editing technology has emerged as a more efficient and precise alternative to these classical approaches. There have been a CRISPR/Cas9 applications to edit the genetic constitution of insects such as S. frugiperda to make them either resistant to pesticides or incorporate gene drives for pest population management. This new genome-editing tool is a tremendous boon for development of long-term sustainable solutions to lessen the effects of fall armyworm on maize. The study reviews recent advances in the application strategies of CRISPR/Cas9 in the target crop plants and the pest species itself to control S. frugiperda. It further provides insight into latest innovation in CRISPR/Cas9 technology related to durable pest resistance and consequences to agricultural sustainability. From this point of view, here we review the features that make CRISPR/Cas9 a tool with the potential to revolutionize pest control approaches.
Schlagworte
biotechnology • maize • gene editing • fall armyworm • pest management